Descripción del proyecto
JAMA - recientes
Mailankody S, Prasad V.
This Viewpoint uses the recent instance of disease awareness promotion on a television soap opera to discuss questions about the role and regulation of novel forms of direct-to-consumer disease awareness marketing.
Mallampati D, Simon MA, Janiak E.
This Viewpoint discusses the importance of US state-based contraceptive and abortion policies given renewed focus by the Trump administration on restrictions to federal funding for reproductive services.
In this Viewpoint, John Ioannidis discusses how the medical community, other scientists, and the public can defend science under the mounting pressure of threatened funding.
This Viewpoint documents the growing market share of direct-to-consumer (DTC) medical testing despite growing recognition that it represents low-value or harmful care and proposes policy options to increase accountability and protect patients from adverse consequences of DTC testing.
Caruso Brown AE.
Each fall, first-year medical students are introduced to the basics of confidentiality. The question is posed: “How many of you would friend a patient?” Watching from the back of the auditorium, I have yet to see a single hand flutter, much less shoot confidently into the air.
Briggs JP, Shurtleff D.
Almost 50 years ago, New York Times reporter James Reston had an emergency appendectomy while traveling in China. His subsequent report that acupuncture produced substantial relief from his postoperative discomfort is widely credited with launching Western interest in acupuncture, although many Western medical practitioners have remained skeptical. Nevertheless, there has been steady progress in application of the methods of evidence-based medicine and modern neuroscience to these ancient practices, suggesting that acupuncture may have therapeutic benefit.
Taichman DB, Sahni P, Pinborg A, et al.
The International Committee of Medical Journal Editors (ICMJE) believes there is an ethical obligation to responsibly share data generated by interventional clinical trials because trial participants have put themselves at risk. In January 2016 we published a proposal aimed at helping to create an environment in which the sharing of deidentified individual participant data becomes the norm. In response to our request for feedback we received many comments from individuals and groups. Some applauded the proposal while others expressed disappointment it did not more quickly create a commitment to data sharing. Many raised valid concerns regarding the feasibility of the proposed requirements, the necessary resources, the real or perceived risks to trial participants, and the need to protect the interests of patients and researchers.
Liu Z, Liu Y, Xu H, et al.
This randomized clinical trial compares the effects of electroacupuncture vs sham electroacupuncture on urinary leakage among women with stress urinary incontinence.
Wu X, Stener-Victorin E, Kuang H, et al.
This 2 × 2 factorial trial compared the effects of active vs sham acupuncture and of clomiphene vs placebo on live births among Chinese women with polycystic ovary syndrome (PCOS).
Wang L, Gao P, Zhang M, et al.
This population epidemiology study uses national survey data to estimate the prevalence and ethnic patterns of diabetes and prediabetes in China in 2013.
Ndumele CD, Schpero WL, Schlesinger MJ, et al.
This study uses Medicaid administrative data to quantify health plan exit from Medicaid managed care between 2006 and 2014 and to evaluate the change in health care quality associated with plan exit.
Litwin MS, Tan H.
This review summarizes advances in risk classification methods, imaging techniques, biomarkers for diagnosis, and treatments for prostate cancer.
This commentary discusses a study published in JAMA Cardiology that examined the association between intensity of statin therapy in patients with atherosclerotic cardiovascular disease and all-cause mortality among patients in the Veterans Affairs health care system.
Martin C, Ledbetter DH.
This Genomics and Precision Health article discusses the advantages of chromosomal microarray analysis over G-banded karotyping for evaluating neurodevelopmental disorders in children.
Cusimano MD, Casey J, Jing R, et al.
This study uses video footage observations of all 64 matches of the 2014 FIFA World Cup to assess the incidence, characteristics, and sideline outcome assessments of player head collisions.
Villamor E, Tedroff K, Cnattingius S.
In Reply Mr Li and Dr Li raise 3 points. First, they note that the analyses did not adjust for important confounding factors including maternal diabetes and hypertension. Gestational diabetes and pregnancy-induced hypertensive diseases are not confounders of the association between early pregnancy BMI and cerebral palsy because they are generally regarded as consequences, not causes, of maternal obesity. Similarly, overweight and obesity increase risks of manifest (type 1 or type 2) diabetes and essential hypertension in a dose-response manner.
Li Y, Li Y.
To the Editor Dr Villamor and colleagues investigated the association between maternal body mass index (BMI) and incidence of cerebral palsy in offspring and found that overweight and obesity in early pregnancy was associated with an increased rate of cerebral palsy. Important confounding factors, including maternal diabetes and hypertension, were not considered in their statistical analyses.
Meesters M, von Heymann C, Boer C.
To the Editor The randomized clinical trial by Dr Bilecen and colleagues showed no benefit of fibrinogen (factor I) concentrate use compared with placebo on intraoperative blood loss in patients with bleeding following high-risk cardiac procedures. We believe that the results may unfairly characterize fibrinogen concentrate use.
Muggleton E, Muggleton T.
To the Editor A number of issues regarding the use of fibrinogen for bleeding during cardiac surgery are raised by the study by Dr Bilecen and colleagues.
Bilecen S, Nierich A.
In Reply Dr Meesters and colleagues are concerned about our choice of primary vs secondary outcomes. In our trial, patients with clinically relevant intraoperative bleeding after removal of cardiopulmonary bypass were randomized to receive placebo or fibrinogen concentrate. The moment of intervention was the start of the primary outcome, ending with closure of the chest. We expected that patients with severe coagulopathic bleeding would have relevant blood loss within this period, so it was chosen as the primary outcome. Because blood loss continues postoperatively, the cumulative 24-hour blood loss was chosen as the secondary outcome.
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